I'm still excited about "The Void" which will be/(is for Cthonian Stars which is already out but under a different system) which is a space setting for Cthulhu. I've been interested in it for a while since I saw it pop up on Yog but I haven't tried it yet. The one thing that really interests me is the setting is supposed to be displayed as hopeful and not grimdark. Though everything is still likely doomed.
Cthulhu Advantus is supposed to be similar, I've listened to some games, it's sort post-apocalyptic dystopia with stargates where the players investigate the horrible things that happened not only to Earth but other places. Not sure how "hard" the sci-fi is supposed to be.